DETAILED NOTES ON LDN-27219 CHEMICAL STRUCTURE

In contrast to neurodegerative conditions and cancer, the contribution of TG2 activity to celiac sprue pathogenesis has long been fairly nicely established. The deamidation of particular glutamine residues targeted by TG2 in gluten peptides is shown to enhance peptide binding towards the disease-related proteins HLA-DQ2/eight, which happen to be th